Logan’s Journey Logan was born 2nd May 2007. He had some health problems since being a baby, but over the previous year, the symptoms got worse, with Logan suffering pains in his stomach and back, which made his legs weak and wobbly. Eventually, a doctor arranged for Logan to go into the local hospital’s children’s ward for investigation. After ultrasound doctors found that Logan had a tumour in his abdomen and diagnosed stage 4 neuroblastoma, he immediately started an 80-day course of chemotherapy. "We were given so much information about treatments and the disease, our heads were spinning!" say Amanda and Ian. Logan had surgery and went on to have high dose chemotherapy. After his chemotherapy, Logan faced a bone marrow transplant and radiotherapy. "I don't know how he keeps going" Logan went from being a funny, happy child, who used to make his friends and family laugh with his funny sayings, to being a frail little boy. He lost a lot of weight following his diagnosis. He regularly experienced high temperatures, which meant frequent stays in hospital and many courses antibiotics. He needed a lot of blood transfusions and platelets, so much so that he became neutropenic. This means that he is very susceptible to infections as his immune stem is weak. His parents know when he is feeling poorly, as he becomes very sleepy, pale and weak. Logan was only four years old when he was diagnosed with neuroblastoma. At the time he had just started school and was making friends, and to his mum, he seemed too young to be going to school. Now, with all he’s been through, his mum feels as if he speaks like he is much older. Amanda said, “I don’t know how he keeps going, just dealing with all the things he has to go through is so hard, but he still always has a smile for us." The family have a lot to deal with. Logan has an older brother Max who has autism. His sister, Amy, aged eight, has Down’s syndrome. Logan’s mum, Amanda, has lupus, an autoimmune disease. This has caused her to have numerous hip and knee replacements. To top it all, Amanda has just broken both of her legs, due to brittle bones caused by lupus. This means that Logan’s dad Ian has had to give up his job to care for the whole family. Treatment Logan didn't respond as hoped to chemotherapy and still had neuroblastoma cells in his bone marrow. Logan was part of a SIOPEN immunotherapy trial taking place in the UK, but his residual disease meant he did not fit the trial criteria. Logan’s oncologist at Manchester Children’s Hospital, told Amanda and Ian that to give Logan the best chance of beating neuroblastoma for good, he needed to receive immunotherapy treatment so the family looked into treatment at the Children’s Hospital of Philadelphia in America. Sadly, Logan missed the time slot to receive immunotherapy treatment in Philadelphia, as treatment on that trial has to begin within 100 days of a bone marrow transplant. While Logan’s family were understandably upset, there is some good news, as Logan was accepted onto a new UK trial which started at Alder Hey Hospital in Liverpool. While this treatment was part of an immunotherapy trial, it was not exactly the same as the treatment Logan would have received in America, where three drugs were used instead of the two that Logan received in Liverpool. Logan’s appeal with Solving Kids' Cancer (then the Neuroblastoma Alliance UK) for treatment costs abroad was put on hold. Any funds raised for Logan were kept for him in his special fund for any further treatment for the next five years.