Research projects

Grant Awarded for Research into Identifying and Treating Chemotherapy-Resistant Neuroblastoma

Solving Kids’ Cancer UK with partners; Solving Kids’ Cancer in New York, Joining Against Cancer in Kids (J-A-C-K), ZOE4LIFE, Merryn Lacy Trust and the Oscar Knox Fund have awarded £500,000 to the Children’s Hospital of Philadelphia (CHOP) and collaborating institutions for research into identifying and treating neuroblastoma in newly diagnosed children that is resistant to current standard chemotherapy. Read more

Landmark Transatlantic Trial for Children with High-Risk Neuroblastoma Funded by Parent-Led Charities

In a landmark in paediatric oncology research, children with high-risk neuroblastoma across Europe and North America will be treated together for the first time. Read more

Grant awarded to open SIOPEN High-Risk Neuroblastoma Clinical Trial 2 across the UK in 2021

Grant Award - High-Risk Neuroblastoma Clinical Trial 2 Read more

Grant awarded to identify markers of poor survival in high-risk neuroblastoma

Solving Kids’ Cancer Europe, Solving Kids' Cancer in New York, Oscar Knox Fund and Merryn Lacy Trust have awarded a grant of $420,000 to co-investigators. Read more

Lorlatinib (PF-06463922) : Third-generation ALK inhibitor

This exciting new clinical trial sees 17 transatlantic centres in the UK, USA and Europe, recruiting patients simultaneously for an innovative new third-generation ALK-inhibitor agent lorlatinib (PF-06463922). Read more

National Neuroblastoma Genetics Reference Centre

The National Neuroblastoma Genetics Reference Centre aims to provide a comprehensive service genetic characterisation of all neuroblastoma tumours at diagnosis and a subset at relapse. Read more

Biomarker evaluation of neuroblastoma mRNAs in children enrolled in the BEACON trial

In this study, blood and bone marrow samples from 120 children treated in the BEACON-Neuroblastoma trial will be collected in order to analyse levels of neuroblastoma mRNAs Read more

MiNivAn : Phase I study of I-131 MIBG, nivolumab and ch14.18/CHO

MiNivAn aims to improve the cure rate of children with relapsed or refractory neuroblastoma by combining targeted radiotherapy (I-131 MIBG) with the antibodies anti-GD2 (ch14.18/CHO) and anti-PD1 (nivolumab). Read more

Neuroblastoma Senior Trials Coordinator

Solving Kids’ Cancer funds a dedicated Senior Trials Coordinator for Neuroblastoma within the Children’s Cancer Trials Team (CCTU) of the Cancer Research UK Clinical Trials Unit (CRCTU), University of Birmingham. Read more

PTPP – ITCC-P4 Collaboration

Bringing together American NCI PPTC and European ITCC-P4 paediatric preclinical research consortiums together for the first time ever via the Pediatric Cancer Working Group at the AACR Annual Meeting. Read more

BEACON Immuno (anti-GD2 amendment)

The BEACON study is a chemotherapy and antibody combination trial. Read more

International Neuroblastoma Research Initiative 2018

Solving Kids’ Cancer is leading an international competitive funding call commencing with a Request for Applications (RFA) Read more

International Research Initiative 2019

Solving Kids’ Cancer has issued a joint 2019 International Challenge Grant Call for GBP 500,000 awarded over three years Read more

Latest

12 hr cycle for Flora - Sunday 25th July 2021

In January 2021 Flora’s parents were given the devastating news that at just 2 years old she had high-level Neuroblastoma, an aggressive childhood cancer.
The 5k Run For Chloe

It is for Chloe to get to Barcelona for her life saving treatment.
Working Together

In the latest edition of her blog our CEO, Gail, shares her experience of being part of the National Neuroblastoma Nursing Group, made up of cancer nurse specialists and research nurses.
Tough mudder and 250 miles for flora

Chloe’s Journey

Chloe was diagnosed with high-risk neuroblastoma at just 2 years old. Chloe is now 10 years old and in February 2020 her parents were given the devastating news that she had relapsed for the second time with her disease progressing in February 2021.
Flora's Campaign

In January 2021 Flora was diagnosed with Autism Spectrum Disorder, and just three months later her parents were given the devastating news she had high-risk neuroblastoma.
Lily-Mae, Ireland’s Tiny Dancer, supports Solving Kids’ Cancer

Lily-Mae from Galway, Ireland will be celebrating her 12th birthday this April, but for her parents Judith and Leighton every day is a blessing.
Ollie’s Appeal

Ollie’s mum and dad are determined to do everything they can to give him the best possible chance of beating neuroblastoma.
Corey is thriving after neuroblastoma battle

Family donate almost £150,000 to neuroblastoma research
Peter's Campaign

11-year-old Peter was diagnosed with neuroblastoma in early 2019. Devastatingly he relapsed in August 2020 after being clear of disease for 6 months. His family are fundraising for further treatment either to get Peter back into remission or to try and keep the cancer away if his treatment goes to plan. This could cost hundreds of thousands of pounds.
Poppy's Campaign

Poppy was diagnosed with high-risk neuroblastoma at just four years old. Her family are fundraising for further treatment, either to get their daughter into remission or to try and keep the cancer away if her frontline treatment does go to plan.
Henry's Urgent Appeal

Henry has high-risk neuroblastoma, an aggressive childhood cancer that has a 40-50% chance of long-term survival at diagnosis. His family are appealing for your help to raise £163,000 by January 2021.
Solving Kids' Cancer welcomes Alexandra Lane to the Board of Trustees

Alexandra Lane was formally voted on and welcomed to our Board of Trustees this week. We are thrilled to welcome Alex to the team.
Nellie-Rose's Campaign

Nellie-Rose is battling a disease no child should have to. She has high-risk neuroblastoma that has a 40-50% chance of long-term survival at diagnosis.